Project News - Rosetta@Home

[Dataman]

Fluorescent proteins designed from scratch


https://boinc.bakerlab.org/rosetta/forum_thread.php?id=12760#89576

[Dataman]

Another publication in Nature describing the first de novo designed proteins with anti-cancer activity.

https://boinc.bakerlab.org/rosetta/forum_thread.php?id=12926#90202

[chooka03]

How what a memory hog Rosetta is!!
Using 89% of my 32 gig.

[Daniel]

The admin at Rosetta@home recently posted some news about Rosetta's role in fighting coronavirus ...

Thank you to all R@h volunteers for your contributions to help accurately model important coronavirus proteins. The collective computing power that you provide through R@h helps academic research groups world wide model important protein structures like these.

From a recent IPD news post:

"We are happy to report that the Rosetta molecular modeling suite was recently used to accurately predict the atomic-scale structure of an important coronavirus protein weeks before it could be measured in the lab. Knowledge gained from studying this viral protein is now being used to guide the design of novel vaccines and antiviral drugs."

Since the release of SARS-CoV-2 genome sequences in late January, a number of important corona virus proteins like the one described above have been modeled on R@h volunteer computers. A list of these proteins is provided by the Seattle Structural Genomics Center for Infectious Disease (SSGCID).

The admin's post is here ...
https://boinc.bakerlab.org/rosetta/forum_thread.php?id=13533

There is a longer article about it here ...
https://www.ipd.uw.edu/2020/02/rosettas-role-in-fighting-coronavirus/

[tazzduke]

Greetings All

I went an had a look at Rosetta@Home again, forums have no moderators, and no real updates/news since 2020, wondering whether Dr Baker and his team are actually running it anymore.  Who Knows?

Due to the computing requirements and lack of news/updates on forums, I don't think I will be crunching this project.

Regards