News:

Members can see all forum boards and posts. Non members can only see a few boards.  If you have forgotten your password use this link to change it.
https://forum.boinc-australia.net/index.php?action=reminder

Main Menu

Project Update

Started by Cruncher Pete, May 06, 2009, 04:47:29 PM

Previous topic - Next topic

chooka03

Gee, I saw the stats come back yesterday and thought YAY... might do some WCG.
Nope... Hardly received a thing.
Thought I might do some Rosetta.... nope... no work.
LHC sixtrack..... nope.... no work.

I'm actually quite happy to save money on the power bill before the next PG challenge thingo.

Hopefully they get WCG sorted soon!

Dingo

I am getting lots of Mapping Cancer Markers from WCG


Radioactive@home graph
Have a look at the BOINC@AUSTRALIA Facebook Page and join and also the Twitter Page.

Proud Founder and member of BOINC@AUSTRALIA

My Luck Prime 1,056,356 digits.
Have a look at my  Web Cam of Parliament House Ottawa, CANADA

chooka03

Oh really?
I still haven't received anything except for 1 OP gpu wu which failed.

Ahh!!! I just found out why!  :banghead  Had the preferences set to no CPU lol.

Seems I've picked up a few Rosetta so I'll finish those up and move onto WCG.

Dingo

WCG is back up and running.


Radioactive@home graph
Have a look at the BOINC@AUSTRALIA Facebook Page and join and also the Twitter Page.

Proud Founder and member of BOINC@AUSTRALIA

My Luck Prime 1,056,356 digits.
Have a look at my  Web Cam of Parliament House Ottawa, CANADA

Dark Angel

Sort of.  I got a bunch of GPU units which all ran for about 8 seconds and come back invalid since there's no data sent in the unit to work on.
I'm still "under moderation" on their forum after being critical of the new site design back before they moved from IBM.  It still looks like someone's 8 yr old kid drew it with blue crayons coz they ate the rest.

tazzduke

Yep, all the other projects, have very interesting websites, but even better badges.

But it's like they did, so they would not offend anyone, cause its very boring, very bland and everything blends in, so yeah, its like you said Dark Angel.

It's such a shame though.

Cheers



 AA 24 - 53 participant

Mick Lindsay

I agree, it seems as they did not take into account the major bandwidth required for the projects. I have not been able to get work from my WCG projects for some time now, but will leave the portal open.



tazzduke

Seems to go in spurts lol



 AA 24 - 53 participant

Dingo

CURRENT PROJECT UPDATES
October 2023


African Rainfall Project

The movement of data from the storage at SURF, a cooperation of educational and
research institutes in The Netherlands, to Amazon Web Services, is almost finished.
All data files have been moved and the final step is to check if indeed the files have
been copied correctly. This is done by comparing so-called hashes, which are a sort
of a digital fingerprint of 128 bits or 16 characters. Even if one bit has changed
during the copying, the hashes on both sides will be different. So far, not a single bit
has gone astray after checking about 300 TB.
The next step is to make the files more easily accessible, which should not take too
long. In the first instance, this will be a list of files and their coordinates and period
covered. ARP team plans that at a later phase the files could be selected more
interactively. What remains for the short term is finishing the last simulations for
which we are very grateful to our volunteers. The expectation is still that all
simulations will be ready by the end of this year.

Help Stop TB

We are excited that the HSTB team has moved locations over the summer to
Loughborough (pronounced luf-bu-rah) University. Loughborough has particular
strengths in AI and machine learning techniques, alongside a strong emphasis on
health, being located nearby one of Astra Zeneca's previous sites in the UK. The
team is hoping that this environment, and the collaborative atmosphere, will help
strengthen the work for the Help Stop TB programme, providing new ideas and
avenues to work on. Whilst the move has created some disruption for the HSTB
project to get back up and running quickly with new work units, these are being
worked on, alongside preparing the existing work for publication. The team has been
transferring the existing scripts to new machines, and undergoing testing to confirm
everything is still compatible and working.

Mapping Cancer Markers

The MCM team's research into lung cancer biomarkers
identified 26 genes with top scores across all signatures
considered. We have been working on characterizing these
genes, including VAMP1, FARP1, GSDMB, and ADH6.
We continue exploring two kinds of sarcoma signatures, one
to distinguish uterine leiomyosarcoma (ULMS) and undifferentiated pleomorphic
sarcoma (UPS) from other histological subtypes, and one to distinguish all 7
histological subtypes in our sarcoma dataset from one another. We ran over 224
million work units for each of these, testing over 7.7 trillion signatures to distinguish
ULMS and UPS from one another, and over 2.7 trillion signatures to distinguish all 7
histological types from one another.
As noted in the September research update, our ovarian cancer results were
dishomogeneous and therefore we have decided to run additional ovarian cancer
work units. On September 26th, the sarcoma project was paused and we restarted
ovarian cancer.
While we perform, improve and expand our analyses of the three types of cancers
run so far, we are looking at the future datasets that will be used for MCM. We are
compiling a priority list that will be shared with volunteers before we proceed.

Open Pandemics

The OPN team has selected about 30 molecules for experimental testing in the lab.
These work units ran over the past few months and docked molecules manufactured
by Enamine, ChemBridge, and ChemDiv. The selection was based on visual
inspection of docked poses and also on whether or not the docked molecules
interact with helicase in a way that resembles the binding mode of known ligands.
These interactions consist mostly of hydrogen bonds and the positioning of polar
groups in the binding pocket. Current work units dock Enamine molecules against
Zika's NS5 protein. Lastly, the team would like to introduce a new member. Manuel
Llanos joined the Forli lab as a postdoctoral researcher and will work on World
Community Grid projects on various fronts, including preparation of work units and
on the analysis of results.

Smash Childhood Cancer

Dr. Hoshino's and Dr. Keller's teams at Chiba University and cc-TDI.org have partial
analysis back from volunteer-generated simulations of drug-protein docking for the
rhabdomyosarcoma protein MyoD1 and the Ewing sarcoma protein FLI1. On the wet
lab side, the compound hits from the PAX-FOXO1 studies computed when WCG
was still supported by IBM have led to a new NIH R03 grant as well as an approved
letter of intent to apply for a CRUK-NCI $25M application (see details here about
Team Koodac).


Radioactive@home graph
Have a look at the BOINC@AUSTRALIA Facebook Page and join and also the Twitter Page.

Proud Founder and member of BOINC@AUSTRALIA

My Luck Prime 1,056,356 digits.
Have a look at my  Web Cam of Parliament House Ottawa, CANADA

Dingo

[World Community Grid] Research update from the MCM team (November 2023)
We continue our work on characterizing lung cancer biomarkers identified in the MCM1 project. This update focuses on IL13RA1, a gene associated with lung cancer survival and differentially expressed across multiple cancer types compared to normal tissues.

View article · Mon, 27 Nov 2023 20:37:12 +0000


Radioactive@home graph
Have a look at the BOINC@AUSTRALIA Facebook Page and join and also the Twitter Page.

Proud Founder and member of BOINC@AUSTRALIA

My Luck Prime 1,056,356 digits.
Have a look at my  Web Cam of Parliament House Ottawa, CANADA

chooka03

Thanks for all these updates Dingo  :thumbsup:
Have a good weekend mate.  :cheers:

Dingo

Quote[World Community Grid] Research update from the MCM team (January 2024)
We continue our work on characterizing lung cancer biomarkers identified in the MCM1 project. This update focuses on PCSK5, a gene associated with lung cancer survival and which shows differential expression across various cancer types.

View article · Tue, 16 Jan 2024 17:18:18 +0000


Radioactive@home graph
Have a look at the BOINC@AUSTRALIA Facebook Page and join and also the Twitter Page.

Proud Founder and member of BOINC@AUSTRALIA

My Luck Prime 1,056,356 digits.
Have a look at my  Web Cam of Parliament House Ottawa, CANADA

Abruraspingi

WCG has another error going on. With Server Error: Feeder not running

So we are unable to upload tasks. The forum users speculate that it won't be up and running until Monday Toronto time.

https://www.worldcommunitygrid.org/forums/wcg/viewthread_thread,46240

Stuff like this is why I keep steering away from WCG. It seems to get better every few months. It's something I guess

Dark Angel

So their server is running on an 8086 with no coprocessor and 65K or RAM with an analogue modem connection.
So inspiring.  :LD  Much "relentless"

Abruraspingi

haha your zingers keep getting better. I still laugh at your blue crayon comment